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International workshop
2022 Joint Pre-ECTRIMS Workshop
Event format
Location & venue

Van Der Valk Zuidas hotel
Tommaso Albinonistraat 200
1083HM Amsterdam

The ECTRIMS endorsed, 2022 Joint Pre-ECTRIMS Workshop is designed for young neurologists and nurses with specific interest in Multiple Sclerosis.

The Med-Ex - EXCEMED Learning Group, in collaboration with the European Charcot Foundation (ECF) and AcademicCME, conducted a live, in presence course that was also accessible via online attendance.  This event was held prior to the ECTRIMS Congress.

academicCME ECF EXCEMED Medex

This Programme took place at 9.30 (CEST), on 25th October, 2022. International experts addressed the main scientific breakthroughs in the field and provided practical suggestions for managing patients in clinical practice.



The field of Multiple Sclerosis (MS) is continuously evolving following the discovery of new pathogenetic mechanisms and new treatment targets. New evidence on MS epidemiology have renovated the interest in viral infections, in particular by Epstein-Barr virus, as main triggers of autoimmune attack to the central nervous system, opening the way for innovative treatment approaches. Recently, new drugs have been licensed for progressive forms of MS, highlighting the need for a more accurate classification of these forms and a better understanding of the mechanisms underpinning disability progression. 

The Pre-ECTRIMS workshop, stemming from a collaboration between EXCEMED-Med-Ex Learning Group, European Charcot Foundation and AcademicCME, aims to provide a yearly update on the main novelties in the most debated themes in the field of MS, through frontal lectures and open discussions involving experts from all over the world.

The workshop was open to in presence and online attendance. 




The slide kits and the video-lectures from this educational activity are available. Please click here to access the resources.




The 2022 joint pre-ECTRIMS workshop, Amsterdam, Netherlands, 25/10/2022 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 4 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.





The 2022 Joint Pre-ECTRIMS Workshop, has been endorsed by ECTRIMS



Learning objectives

  • Describe new immunological mechanisms underpinning MS
  • Illustrate mechanisms of action and safety profile of new MS treatments
  • Describe emerging environmental factors influencing MS development
  • Discuss how to identify and monitor disability progression


AGENDA - Day 1 - October 25th, 2022

9.30 Welcome & Opening

G. Comi (Italy) and F. Lublin (USA)


Session 1: Understanding Multiple Sclerosis

Chair: G Comi (Italy)


9.45 L1 - Updated MS immunology

Bar-Or (USA)


10.05 L2 - New Diagnostic and prognostic aspects 

M. Tintorè (Spain)


10.25 L3 - Emerging treatments for relapsing and progressive MS 

G. Comi (Italy)


10.45 L4 - Remote monitoring in MS
L. Leocani (Italy)


11.05 Q&A


11.25 Coffee Break 

Session 2: Epstein-Barr virus in MS

Chairs: G Comi (Italy) and H. Lassmann (Austria)


11.45 L5 - Epidemiology 

A. Ascherio (USA)


12.05 L6 - Immunopathogenesis 

F. Aloisi (Italy)


12.25 L7 -  Possible interventions 

H. P. Hartung (Germany)


12.45 Q&A


13.05 Lunch 


Session 3: Controversies in Multiple Sclerosis Care
How MS Patients Develop Disability: Our New Understanding of the Role of Relapses and Progression

Chair: F D Lublin, (USA)


14.10 L8 - PIRA - What is it? How Does it Develop? 

L Kappos (Switzerland)


14.30 L9 - Developing Disability - Reassessing the Spectrum of MS

F.D. Lublin (USA)


14.50 L10 - Visualizing the Clinical Course of MS Over Time 

S. Krieger (USA)


15.10 L11 - Imaging Progressive Disease 

M. Inglese (Italy)


15.30        Q&A




15.50    Scientific Update on Bruton Tyrosine Kinase Inhibitors to Improve Outcomes for Patients with Multiple Sclerosis

B.M. Greenberg (USA)

16.50   Strategies to Identify and Manage Spasticity and Related Symptoms in Patients with Multiple Sclerosis

F.D. Lublin (USA)


17.50   Wrap up


18.00 End of the day



MS Center, Neurorehabilitation Department Casa di Cura Igea
Milan, Italy
Gallarate Hospital Gallarate, Italy
Saunders Family Professor of Neurology
The Corinne Goldsmith Dickinson Centre for Multiple Sclerosis
Icahn School of Medicine at Mount Sinai
New York, USA


Contact Alessia Addessi if you have questions or need support.


MS Center, Neurorehabilitation Department Casa di Cura Igea
Milan, Italy
Gallarate Hospital Gallarate, Italy
Saunders Family Professor of Neurology
The Corinne Goldsmith Dickinson Centre for Multiple Sclerosis
Icahn School of Medicine at Mount Sinai
New York, USA
Multiple Sclerosis Division Department of Neurology
Perelman School of Medicine and
Center for Neuroinflammation and Neurotherapeutics Children’s Hospital of Pennsylvania
Philadelphia, USA
Neurology-Neuroimmunology Department Multiple Sclerosis Centre of Catalonia (Cemcat)
Vall d’Hebron University Hospital
Barcelona, Spain
Institute of Experimental Neurology University Vita-Salute IRCCS
Milan, Italy
Department of Epidemiology and Nutrition Harvard
T.H. Chan School of Public Health
Boston, USA
Department of Neuroscience
Istituto Superiore di Sanità
Rome, Italy
Center for Neuropsychiatry
Department of Neurology Heinrich-Heine-University Dusseldorf
Dusseldorf, Germany
Department of Biomedicine
University Hospital Basel
Basel, Switzerland
Associate Professor of Neurology
University of Genoa
Genoa, Italy
Department of Neurology and Neurotherapeutics
UT Southwestern Medical Center
Dallas, USA
The Corinne Goldsmith Dickinson Centre for MS at Mount Sinai
New York, USA
Division of Neuroimmunology
Center for Brain Research
Medical University of Wien
Wien, Austria